I'm still looking for a decent chatbot system with full audio and video compatibility with Skype.
There is a huge amount of confusion online when people talk about chatbots and Skype.  Chatbots have a long history of IM/XMPP compatibility.  Skype, like Facebook, has an auxiliary IM channel.  I am completely uninterested in IM chatbots for either Skype or Facebook.  I expect full human-like interactivity on social channels.  For instance, on Facebook this would mean proactive timeline posting and reactive commenting, as well as perhaps PM (rather than IM).
I don't know anything about Twitch, but it sounds like IM me.